Dr. Sajad Zalzala | Exploring the Science of Healthy Aging and Longevity MedicineWelcome to a physician’s perspective on the cutting edge of longevity medicine. I’m Dr. Sajad Zalzala—physician, researcher, and co-founder of AgelessRx—and I’ve spent two decades working at the intersection of clinical practice, digital health innovation, and aging science. From co-investigating the world’s first large-scale rapamycin trial to advising healthcare startups on metabolic optimization and preventive care, my work centers on one fundamental question: How do we not just live longer, but live better?
This site is where I share insights from the front lines of longevity research, functional medicine protocols that address root causes rather than symptoms, and practical strategies for optimizing health across the lifespan. Whether you’re curious about emerging interventions, metabolic health, or the science behind healthy aging, you’ll find evidence-based perspectives grounded in real-world clinical experience.
Let’s explore what it truly means to age well.
This site is for anyone curious about the science of aging and committed to taking control of their healthspan. Whether you're a biohacker exploring cutting-edge interventions, a healthcare professional seeking evidence-based protocols, a patient frustrated by symptom-focused medicine, or simply someone who wants to understand how to age with vitality—you'll find practical insights rooted in clinical experience and peer-reviewed research. If you believe health optimization goes beyond treating disease, if you're willing to address root causes rather than chase quick fixes, and if you want information you can trust from someone working at the forefront of longevity medicine, this is your resource.
Dr. Sajad Zalzala is a board-certified physician, researcher, and entrepreneur who has dedicated his career to advancing longevity and functional medicine. As co-founder and former Chief Medical Officer of AgelessRx, he helped pioneer telemedicine-based longevity interventions and served as co-investigator on the PEARL trial—the world’s first large-scale clinical trial of rapamycin for aging. His team also won the inaugural round of the XPRIZE Healthspan competition.
His work spans bone health optimization, metabolic care, cancer prevention, chronic pain management, and immune system support—always with an eye toward extending healthspan, not just lifespan.
Currently, Dr. Z leads Root Causes Medical, where he delivers personalized longevity-focused care while advising healthcare startups on metabolic health, preventive medicine, and digital health innovation. Licensed in all 50 states, he combines two decades of clinical practice with deep expertise in functional medicine, working to help patients and organizations move beyond conventional approaches to address the true drivers of health and disease.
Longevity medicine represents a fundamental shift in how we approach healthcare. Rather than waiting for diseases to develop and then treating symptoms, longevity medicine targets the underlying biological mechanisms of aging itself. The field focuses on extending healthspan—the years we live in good health—rather than simply adding years to life.
The distinction is crucial: living to 90 with two decades of declining health is very different from living to 90 with vitality, independence, and cognitive sharpness. Longevity medicine aims for the latter.
Introduction: The Dawn of Regenerative Medicine – Precision Gerontology and AI The field of regenerative medicine has experienced a dramatic shift in recent years, moving
Introduction The traditional understanding of aging has long been centered around the slowing of biological processes – a gradual decline in cellular function and overall
Introduction The relentless march of time brings with it a growing awareness of the complexities of aging and the desire to extend healthy lifespan. While
Introduction The human experience is fundamentally shaped by sleep. Often relegated to a passive state of rest, sleep is in reality a profoundly active and
Introduction The human lifespan has dramatically increased over the past century, a testament to advancements in medicine and public health. However, the experience of aging
Introduction The relentless march of time inevitably leads to subtle changes in our bodies – wrinkles, reduced elasticity, and a general slowing of function. Says Dr.
This is a non-commercial educational resource dedicated to sharing evidence-based perspectives on longevity, functional medicine, and healthspan optimization. The content provided is for informational purposes only and does not constitute medical advice. Always consult with a qualified healthcare provider before making changes to your health regimen.
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